The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2015

Filed:

Aug. 26, 2009
Applicants:

Thomas A. Mustoe, Evanston, IL (US);

Nicholas M. Dean, Encinitas, CA (US);

Mark Sisco, New York, NY (US);

Zol Kryger, Agoura Hills, CA (US);

C. Frank Bennett, Carlsbad, CA (US);

Inventors:

Thomas A. Mustoe, Evanston, IL (US);

Nicholas M. Dean, Encinitas, CA (US);

Mark Sisco, New York, NY (US);

Zol Kryger, Agoura Hills, CA (US);

C. Frank Bennett, Carlsbad, CA (US);

Assignees:

Excaliard Pharmaceuticals, Inc., New York, NY (US);

Isis Pharmaceuticals, Inc., Carlsbad, CA (US);

Northwestern University, Evanston, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides a method for reducing hypertropic scarring resulting from dermal wound healing in a subject in need which comprises administering to the subject an antisense oligonucleotide which inhibits expression of connective tissue growth factor (CTGF) in an amount effective to inhibit expression of CTGF and thereby reduce hypertrophic scarring.


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