The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 03, 2015
Filed:
Jul. 20, 2011
Applicants:
Hongwen M. Rivers, San Diego, CA (US);
Lon T. Spada, Walnut, CA (US);
Michelle Luu, Anaheim, CA (US);
Inventors:
Hongwen M. Rivers, San Diego, CA (US);
Lon T. Spada, Walnut, CA (US);
Michelle Luu, Anaheim, CA (US);
Assignee:
Allergan, Inc., Irvine, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/34 (2006.01); A61K 48/00 (2006.01); A61K 9/00 (2006.01); A61K 31/7088 (2006.01); A61K 31/713 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0075 (2013.01); A61K 9/0051 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 47/34 (2013.01); A61K 47/48046 (2013.01); A61K 47/48323 (2013.01);
Abstract
An ocular implant comprising siRNA complexed with a transfection agent selected from the group consisting of cationic lipids and short cell penetration peptides, wherein the complex is associated with a biocompatible polymer is described. The biocompatible polymer comprises a polymeric matrix configured to release the complex into the eye of a patient at therapeutic levels for a time sufficient to treat an ocular condition or disease.