The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2015

Filed:

Aug. 13, 2012
Applicants:

Norihiko Shiraishi, Tokyo, JP;

Akiko Furuya, Tokyo, JP;

Hiroe Toki, Tokyo, JP;

Hiroshi Ando, Tokyo, JP;

Masayo Suzuki, Tokyo, JP;

Tsuguo Kubota, Tokyo, JP;

Inventors:

Norihiko Shiraishi, Tokyo, JP;

Akiko Furuya, Tokyo, JP;

Hiroe Toki, Tokyo, JP;

Hiroshi Ando, Tokyo, JP;

Masayo Suzuki, Tokyo, JP;

Tsuguo Kubota, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12N 15/13 (2006.01); C12N 15/63 (2006.01); C12N 5/07 (2010.01); C12N 5/10 (2006.01); C12N 5/12 (2006.01); C07K 16/28 (2006.01); G01N 33/68 (2006.01); C07K 16/30 (2006.01); G01N 33/574 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); C12N 15/09 (2013.01); C07H 21/04 (2013.01); C12N 5/12 (2013.01); G01N 33/6893 (2013.01); C07K 2317/33 (2013.01); C07K 2317/565 (2013.01); C07K 16/28 (2013.01); C07K 2317/734 (2013.01); C12N 15/63 (2013.01); C07K 2317/56 (2013.01); C07K 2317/732 (2013.01); A61K 39/39533 (2013.01); A61K 2039/505 (2013.01); C07K 2317/73 (2013.01); C12N 2800/10 (2013.01); G01N 33/574 (2013.01); G01N 33/6872 (2013.01);
Abstract

An object of the present invention is to provide a monoclonal antibody which is useful for treating or diagnosing a disease relating to system ASC amino acid transporter 2 (hereinafter, referred to as 'ASCT2') or a method using the antibody. The present invention provides a monoclonal antibody which specifically recognizes a native three-dimensional structure of an extracellular region of ASCT2 and binds to the extracellular region, or an antibody fragment thereof; a hybridoma which produces the antibody; a DNA which encodes the antibody; a vector which contains the DNA; a transformant obtainable by introducing the vector; a process for producing an antibody or an antibody fragment thereof using the hybridoma or the transformant; and a therapeutic agent using the antibody or the antibody fragment thereof, and a diagnostic agent using the antibody or the antibody fragment thereof.


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