The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2015

Filed:

Aug. 02, 2012
Applicants:

Ryan D. Bomgarden, Winnebago, IL (US);

Eric Leigh Hommema, Roscoe, IL (US);

John Charles Rogers, Rockton, IL (US);

Penny Joann Jensen, Marengo, IL (US);

Derek Karl Baerenwald, Minneapolis, MN (US);

Inventors:

Ryan D. Bomgarden, Winnebago, IL (US);

Eric Leigh Hommema, Roscoe, IL (US);

John Charles Rogers, Rockton, IL (US);

Penny JoAnn Jensen, Marengo, IL (US);

Derek Karl Baerenwald, Minneapolis, MN (US);

Assignee:

Pierce Biotechnology, Inc., Rockford, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/00 (2006.01); G01N 33/566 (2006.01); G01N 25/00 (2006.01); G01N 33/68 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
C12P 21/02 (2013.01); G01N 33/6848 (2013.01); G01N 2560/00 (2013.01);
Abstract

Methods for producing an isotope-labeled mammalian, including a human, biomolecule, such as polypeptides and proteins, in a cell-free protein synthesis system. A biomolecule standard is produced having at least one isotope different in abundance than that of the naturally occurring isotopes in the biomolecule. Methods for quantifying biomolecules standards expressed using mammalian cell-free extracts are disclosed. Methods for producing such standards, kits, systems and reagents, relating to the use of isotope-labeled biomolecule as quantification standards in mass spectrometric and nuclear magnetic resonance analysis.


Find Patent Forward Citations

Loading…