The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2015

Filed:

Feb. 06, 2013
Applicant:

Vaxinnate Corporation, Cranbury, NJ (US);

Inventors:

Langzhou Song, Cranbury, NJ (US);

Valerian Nakaar, Cranbury, NJ (US);

Albert E. Price, Cranbury, NJ (US);

Lynda G. Tussey, Cranbury, NJ (US);

James W. Huleatt, Cranbury, NJ (US);

Thomas J. Powell, Cranbury, NJ (US);

Robert K. Evans, Cranbury, NJ (US);

Assignee:

VaxInnate Corporation, Cranbury, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/145 (2006.01); C07K 14/11 (2006.01); A61K 39/02 (2006.01); A61K 39/108 (2006.01); A61K 39/12 (2006.01); A61K 39/385 (2006.01); C07K 14/005 (2006.01); C07K 14/195 (2006.01); C07K 14/255 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/11 (2013.01); A61K 39/02 (2013.01); A61K 39/0258 (2013.01); A61K 39/12 (2013.01); A61K 39/145 (2013.01); A61K 39/385 (2013.01); C07K 14/005 (2013.01); C07K 14/195 (2013.01); C07K 14/255 (2013.01); A61K 39/00 (2013.01); A61K 2039/6018 (2013.01); A61K 2039/6037 (2013.01); A61K 2039/6068 (2013.01); A61K 2039/6075 (2013.01); C07K 2319/00 (2013.01); C12N 2760/16122 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16222 (2013.01); C12N 2760/16234 (2013.01); C12N 2770/24122 (2013.01);
Abstract

Methods that stimulate a protective immune response in a subject include a portion of a protein from a naturally occurring viral hemagglutinin, wherein the protein portion includes at least a portion of a globular head and at least a portion of at least one secondary structure that causes the globular head to essentially retain its tertiary structure, and wherein the protein portion lacks a transmembrane domain, a cytoplasmic domain and an HA2 subunit. Compositions administered to the subject can further include a carrier and can be administered in single or multiple doses.


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