The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2015

Filed:

Aug. 17, 2010
Applicants:

Ekkehard Mössner, Kreuzlingen, CH;

Ralf Jörg Hosse, Bonstetten, CH;

Pablo Umaña, Wädenswil, CH;

Michela Silacci-melkko, Zürich, CH;

Inventors:

Ekkehard Mössner, Kreuzlingen, CH;

Ralf Jörg Hosse, Bonstetten, CH;

Pablo Umaña, Wädenswil, CH;

Michela Silacci-Melkko, Zürich, CH;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C12N 15/00 (2006.01); C12N 5/10 (2006.01); C12P 21/08 (2006.01); C07K 16/46 (2006.01); C07H 21/04 (2006.01); C07K 16/00 (2006.01); A61K 47/48 (2006.01); C07K 16/18 (2006.01); C07K 16/40 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/00 (2013.01); A61K 47/48423 (2013.01); A61K 47/48538 (2013.01); A61K 47/48646 (2013.01); C07K 16/18 (2013.01); C07K 16/40 (2013.01); C07K 16/468 (2013.01); A61K 2039/505 (2013.01); C07K 2317/73 (2013.01); C07K 2317/74 (2013.01); C07K 2317/92 (2013.01);
Abstract

The present invention relates to immunoconjugates. In particular embodiments, the present invention relates to immunoconjugates comprising at least one single-chain effector moiety and two or more antigen binding moieties. In addition, the present invention relates to nucleic acid molecules encoding such immunoconjugates, vectors and host cells comprising such nucleic acid molecules. The invention further relates to methods for producing the immunoconjugates of the invention, and to methods of using these immunoconjugates in the treatment of disease.


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