The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2015

Filed:

Nov. 19, 2010
Applicants:

Austin L. Gurney, San Francisco, CA (US);

Timothy Charles Hoey, Hillsborough, CA (US);

Aaron Ken Sato, Burlingame, CA (US);

Alexandra Lazetic, San Jose, CA (US);

Zhimin Ji, Palo Alto, CA (US);

Inventors:

Austin L. Gurney, San Francisco, CA (US);

Timothy Charles Hoey, Hillsborough, CA (US);

Aaron Ken Sato, Burlingame, CA (US);

Alexandra Lazetic, San Jose, CA (US);

Zhimin Ji, Palo Alto, CA (US);

Assignee:

OncoMed Pharmaceuticals, Inc., Redwood City, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2896 (2013.01); A61K 39/3955 (2013.01); A61K 2039/505 (2013.01); C07K 317/73 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

Antibodies that specifically bind to an extracellular domain of human Jagged 1 or human Jagged2 and modulate Jagged activity, and methods of using said antibodies to inhibit tumor growth are disclosed. Also described are methods of treating cancer comprising administering a therapeutically effect amount of an anti-Jagged antibody to a patient having a tumor or cancer.


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