The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2015

Filed:

Apr. 26, 2012
Applicants:

Birgit C. Schultes, Arlington, MA (US);

Christopher F. Nicodemus, Charlestown, MA (US);

Inventors:

Birgit C. Schultes, Arlington, MA (US);

Christopher F. Nicodemus, Charlestown, MA (US);

Assignee:

Quest PharmaTech, Inc., Alberta, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); A61K 39/395 (2013.01); A61K 2039/555 (2013.01); C07K 2317/52 (2013.01); Y10S 424/805 (2013.01); Y10S 530/862 (2013.01);
Abstract

The invention provides a method for increasing the bioactivity (e.g. the biosafety and efficacy) of a therapeutic IgE antibody of the invention in the treatment of a patient. Methods of the invention include: i) administering to the patient a therapeutic IgE antibody in combination with at least one bioactivity-enhancing agent, ii) strategic treatment regimens and protocols for the dosing and administration of a therapeutic IgE antibody of the invention, and iii) the use of a therapeutic IgE antibody having a variable region comprising at least one antigen binding region specific for binding an epitope of an antigen wherein the epitope is not highly repetitive or is non-repetitive.


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