The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2015

Filed:

Apr. 17, 2007
Applicants:

Xiaofeng LU, Fremont, CA (US);

Bao-lu Chen, San Ramon, CA (US);

Kidisti Araya, Berkeley, CA (US);

Augustus Okhamafe, Concord, CA (US);

Inventors:

Xiaofeng Lu, Fremont, CA (US);

Bao-Lu Chen, San Ramon, CA (US);

Kidisti Araya, Berkeley, CA (US);

Augustus Okhamafe, Concord, CA (US);

Assignees:

Novartis AG, Basel, CH;

Xoma Technology Ltd., Berkeley, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); C07K 2316/96 (2013.01);
Abstract

Stable liquid pharmaceutical compositions comprising an antagonist anti-CD40 antibody as a therapeutically or prophylactically active component and methods useful in their preparation are provided. These compositions comprise the antagonist anti-CD40 antibody, a buffering agent to maintain the pH of the composition between about pH 5.0 and about pH 7.0, and an amount of arginine-HCl sufficient to render the liquid composition near isotonic. The stable liquid antagonist anti-CD40 antibody-containing pharmaceutical compositions of the invention find use in methods for treating proliferative diseases and diseases having an autoimmune and/or inflammatory component.


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