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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8945512 B1

PDFFull Text
Expired
Date of Patent:
Feb. 03, 2015

Filed:

Apr. 06, 2004

Adducts between magnetic resonance shift reagents and substrates containing exchangeable protons for 'cest' applications

Applicants:

Silvio Aime, Milan, IT;

Enzo Terreno, Milan, IT;

Daniela Delli Castelli, Milan, IT;

Giovanni Battista Giovenzana, Milan, IT;

Inventors:

Silvio Aime, Milan, IT;

Enzo Terreno, Milan, IT;

Daniela Delli Castelli, Milan, IT;

Giovanni Battista Giovenzana, Milan, IT;

Assignee:

Bracco Imaging SpA, Milan, IT;

Attorney:

Robert E. Alderson, Jr.

Primary Examiner:

Michael G Hartley

Assistant Examiner:

Lance Rider

Int. Cl.
CPC ...
A61B 5/055 (2006.01); A61B 5/00 (2006.01); C07K 1/00 (2006.01); C08B 37/00 (2006.01); A61K 49/08 (2006.01); A61K 49/10 (2006.01); A61K 49/14 (2006.01);
U.S. Cl.
CPC ...
A61K 49/085 (2013.01); A61K 49/10 (2013.01); A61K 49/146 (2013.01);
Abstract

Disclosed are CEST paramagnetic agents comprising a substrate (SH) containing mobile protons bonded to a paramagnetic chelate (SR) containing a metal selected from iron (11) (high-spin configuration), iron (111), cobalt (11), rhodium (11), copper (11), nickel (11), cerium (111), praseodymium (111), neodymium (111), dysprosium (111), erbium (111), terbium (111), holmium (111), thulium (III), ytterbium (III) and europium (111).

Find Patent Forward Citations

Aime, Silvio. (2015). Adducts between magnetic resonance shift reagents and substrates containing exchangeable protons for 'cest' applications (U.S. Patent No. 8945512). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8945512

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