The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 03, 2015
Filed:
Apr. 06, 2004
Applicants:
Silvio Aime, Milan, IT;
Enzo Terreno, Milan, IT;
Daniela Delli Castelli, Milan, IT;
Giovanni Battista Giovenzana, Milan, IT;
Inventors:
Silvio Aime, Milan, IT;
Enzo Terreno, Milan, IT;
Daniela Delli Castelli, Milan, IT;
Giovanni Battista Giovenzana, Milan, IT;
Assignee:
Bracco Imaging SpA, Milan, IT;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/055 (2006.01); A61B 5/00 (2006.01); C07K 1/00 (2006.01); C08B 37/00 (2006.01); A61K 49/08 (2006.01); A61K 49/10 (2006.01); A61K 49/14 (2006.01);
U.S. Cl.
CPC ...
A61K 49/085 (2013.01); A61K 49/10 (2013.01); A61K 49/146 (2013.01);
Abstract
Disclosed are CEST paramagnetic agents comprising a substrate (SH) containing mobile protons bonded to a paramagnetic chelate (SR) containing a metal selected from iron (11) (high-spin configuration), iron (111), cobalt (11), rhodium (11), copper (11), nickel (11), cerium (111), praseodymium (111), neodymium (111), dysprosium (111), erbium (111), terbium (111), holmium (111), thulium (III), ytterbium (III) and europium (111).