The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 03, 2015

Filed:

Aug. 24, 2012
Applicants:

Paul B. Savage, Mapleton, UT (US);

Roy D. Bloebaum, Salt Lake City, UT (US);

Dustin L. Williams, Bountiful, UT (US);

Kristofer D. Sinclair, Salt Lake City, UT (US);

Bryan S. Haymond, Salt Lake City, UT (US);

Inventors:

Paul B. Savage, Mapleton, UT (US);

Roy D. Bloebaum, Salt Lake City, UT (US);

Dustin L. Williams, Bountiful, UT (US);

Kristofer D. Sinclair, Salt Lake City, UT (US);

Bryan S. Haymond, Salt Lake City, UT (US);

Assignees:

Brigham Young University, Provo, UT (US);

University of Utah Research Foundation, Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61F 2/02 (2006.01); A01N 45/00 (2006.01); A01N 25/10 (2006.01); A61L 27/34 (2006.01); A61L 27/54 (2006.01);
U.S. Cl.
CPC ...
A01N 45/00 (2013.01); A01N 25/10 (2013.01); A61F 2/02 (2013.01); A61L 27/34 (2013.01); A61L 27/54 (2013.01); A61L 2300/404 (2013.01);
Abstract

A medical device that includes a coating of a composite material that includes a polymeric material having a void structure and particulate ceragenin material (i.e., ceragenin particles) associated with the void structure. The average particle size of the ceragenin particles in the composite is in a range from 5 nm to 20 μm, 50 nm to 10 μm, 100 nm to 5 Ξm, or 1 μm to 10 μm. The composite has a high loading of ceragenin particles (e.g., about 10% to about 25%, by weight). The composite has good polymer stability, the ability to release ceragenins from the ceragenin particles disposed in the composite over a sustained period of time at a characteristic elution rate, and the ability to kill large numbers of bacteria and other susceptible microbes over the sustained period of time.


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