The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 27, 2015
Filed:
Aug. 01, 2013
Yan-yeung Luk, Jamesville, NY (US);
Sri Kamesh Narasimhan, Syracuse, NY (US);
Eric Falcone, Syracuse, NY (US);
Yan-Yeung Luk, Jamesville, NY (US);
Sri Kamesh Narasimhan, Syracuse, NY (US);
Eric Falcone, Syracuse, NY (US);
Syracuse University, Syracuse, NY (US);
Abstract
A library of unnatural squarylated homoserine lactones (SHLs) and squarylated lactones that bear potential to modulate biofilm formation in Gram negative bacteria. At low concentrations (˜200 μM), these small molecules inhibit biofilm formation of. Moreover, these compounds are not toxic up to 300 μM and do not significantly attenuategrowth. The SHLs have potential to disperse established biofilm and demonstrate an enhanced reduction (˜50%) of the maximum biofilm thickness by use of SHLs during biofilm growth.