The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 27, 2015
Filed:
Nov. 26, 2013
Applicant:
University of Kentucky Research Foundation, Lexington, KY (US);
Inventors:
Peter Crooks, Little Rock, AR (US);
Linda Dwoskin, Lexington, KY (US);
Roger Papke, Gainesville, FL (US);
Guangrong Zheng, Lexington, KY (US);
Sangeetha Sumithran, Lexington, KY (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/47 (2006.01); A61K 31/44 (2006.01); A61K 31/445 (2006.01); A61K 31/53 (2006.01); A61K 31/40 (2006.01); A61K 31/41 (2006.01); A61K 31/415 (2006.01); C07D 217/00 (2006.01); C07D 213/04 (2006.01); C07D 401/00 (2006.01); C07D 215/10 (2006.01); C07D 215/12 (2006.01); C07D 213/06 (2006.01); C07D 213/02 (2006.01); C07D 215/06 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 217/04 (2006.01); A61K 31/50 (2006.01); A61K 31/497 (2006.01);
U.S. Cl.
CPC ...
C07D 213/06 (2013.01); C07D 213/02 (2013.01); C07D 215/06 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 217/04 (2013.01);
Abstract
Provided are tris-quaternary ammonium compounds which are modulators of nicotinic acetylcholine receptors. Also provided are methods of using the compounds for modulating the function of a nicotinic acetylcholine receptor, and for the prevention and/or treatment of central nervous system disorders, substance use and/or abuse and/or gastrointestinal tract disorders.