The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 27, 2015
Filed:
Nov. 03, 2004
Applicants:
Volker Sandig, Berlin, DE;
Ingo Jordan, Berlin, DE;
Inventors:
Volker Sandig, Berlin, DE;
Ingo Jordan, Berlin, DE;
Assignee:
Probiogen AG, Berlin, DE;
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/16 (2006.01); C07K 14/005 (2006.01); A61K 39/12 (2006.01); A61K 48/00 (2006.01); C12N 5/073 (2010.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); A61K 39/12 (2013.01); A61K 48/0091 (2013.01); C12N 5/0603 (2013.01); C12N 7/00 (2013.01); C12N 2710/10222 (2013.01); C12N 2710/10252 (2013.01); C12N 2710/10322 (2013.01); C12N 2710/10352 (2013.01); C12N 2710/24122 (2013.01);
Abstract
The present invention relates to immortalized avian cell lines suitable for production of biologicals or viruses for vaccination. In particular, the cell lines are derived from primary cells which are transformed with at least two viral or cellular genes, one of which causes cell cycle progression whereas the other interferes with innate protective mechanisms of the cell induced by dysregulated replication. The invention moreover relates to the production of said immortalized cell lines and their use for producing biologicals or viruses for vaccination.