The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 27, 2015
Filed:
Feb. 01, 2013
Applicant:
Butamax™ Advanced Biofuels Llc, Wilmington, DE (US);
Inventor:
Robert A. LaRossa, Chadds Ford, PA (US);
Assignee:
Butamax Advanced Biofuels LLC, , DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/16 (2006.01); C12N 1/19 (2006.01);
U.S. Cl.
CPC ...
Abstract
Yeast cells with a reduced general control response to amino acid starvation were found to have increased tolerance to butanol in the growth medium. The reduced response was engineered by genetic modification of a gene involved in the response, a GCN gene, to eliminate activity of the encoded protein. Yeast strains with an engineered butanol biosynthetic pathway and a genetic modification in a gene involved in the general control response to amino acid starvation, which have increased butanol tolerance, are useful for production of butanol.