The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 27, 2015
Filed:
Jan. 14, 2009
Applicants:
Ann-hwee Lee, Chestnut Hill, MA (US);
Laurie H. Glimcher, New York, NY (US);
Inventors:
Ann-Hwee Lee, Chestnut Hill, MA (US);
Laurie H. Glimcher, New York, NY (US);
Assignee:
Cornell University, Ithaca, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); A61K 31/70 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 31/70 (2013.01); C12N 15/113 (2013.01); C12N 2310/14 (2013.01); G01N 2333/4703 (2013.01); G01N 2500/04 (2013.01); G01N 2800/044 (2013.01);
Abstract
The invention provides methods and compositions for modulating the expression, processing, post-translational modification, stability and/or activity of XBP-1 protein, or a protein in a signal transduction pathway involving XBP-I to treat dyslipidemias and steatosis disorders. The present invention also pertains to methods for identifying compounds that modulate the expression, processing, post-translational modification, and/or activity of XBP-I protein or a molecule in a signal transduction pathway involving XBP-1.