The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 27, 2015

Filed:

May. 16, 2007
Applicants:

Masayuki Kitagawa, Kita-ku, JP;

Keizou Ishikawa, Kita-ku, JP;

Keiichirou Yamamoto, Kita-ku, JP;

Kazutoshi Takashio, Kita-ku, JP;

Masao Shibata, Kita-ku, JP;

Inventors:

Masayuki Kitagawa, Kita-ku, JP;

Keizou Ishikawa, Kita-ku, JP;

Keiichirou Yamamoto, Kita-ku, JP;

Kazutoshi Takashio, Kita-ku, JP;

Masao Shibata, Kita-ku, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 31/7048 (2006.01); A61K 9/00 (2006.01); A61K 31/365 (2006.01); A61K 47/48 (2006.01); C08G 65/331 (2006.01); C08G 65/332 (2006.01); C08G 73/10 (2006.01); C08G 83/00 (2006.01); C08L 71/02 (2006.01); A61K 47/26 (2006.01); C08L 77/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7048 (2013.01); A61K 9/0019 (2013.01); A61K 31/365 (2013.01); A61K 47/48215 (2013.01); C08G 65/331 (2013.01); C08G 65/3314 (2013.01); C08G 65/3324 (2013.01); C08G 73/1092 (2013.01); C08G 83/00 (2013.01); C08L 71/02 (2013.01); A61K 47/26 (2013.01); C08L 77/00 (2013.01); C08L 2203/02 (2013.01); C08L 2205/05 (2013.01);
Abstract

A novel podophyllotoxin derivative, which is capable of releasing a drug without depending on biological enzymes and can be expected to have an effective therapeutic effect and is soluble in water has been demanded. A polymer having a polyethyleneglycol structural unit and two or more succinic monoamide structural units, particularly a polymer conjugate of a podophyllotoxin in which a carboxylic acid group of polyethyleneglycol/polyaspartic acid copolymer and a hydroxyl group of podophyllotoxin and linked via an ester bond is provided.


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