The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 20, 2015

Filed:

Aug. 06, 2007
Applicants:

Takashi Miyata, Suita, JP;

Tadashi Uragami, Suita, JP;

Kaori Okawa, Gifu, JP;

Inventors:

Takashi Miyata, Suita, JP;

Tadashi Uragami, Suita, JP;

Kaori Okawa, Gifu, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); B01D 57/02 (2006.01); C12Q 1/68 (2006.01); C12P 19/34 (2006.01); G01N 33/00 (2006.01); C07H 21/02 (2006.01); G01N 15/06 (2006.01); G01N 33/48 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6816 (2013.01); C12Q 1/6816 (2013.01); C12Q 2565/625 (2013.01); C12Q 2565/518 (2013.01); C12Q 2523/101 (2013.01);
Abstract

The present invention provides a nucleic-acid-responsive gel which allows (i) a larger volumetric change through structural design, (ii) adjustment of its recognition ability to recognize a nucleic acid, (iii) improvement of sensitivity, and (iv) flexible design according to, e.g., a sequence of target DNA. The nucleic-acid-responsive gel includes a probe formed of two single-stranded nucleic acids which are hybridized with each other. The probe is fixed within a network structure of a polymer gel. The two single-stranded nucleic acids are bound reversibly with each other.


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