The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 20, 2015

Filed:

Oct. 17, 2011
Applicants:

David Joseph Guerin, Natick, MA (US);

Jason D. Brubaker, Cambridge, MA (US);

Michelle Martinez, Medford, MA (US);

Joon O. Jung, Newton, MA (US);

Neville J. Anthony, Northborough, MA (US);

Mark E. Scott, Andover, MA (US);

Carolyn Michele Cammarano, Worcestor, MA (US);

Dawn Marie Mampreian Hoffman, Boston, MA (US);

Hyun Chong Woo, Natick, MA (US);

Christopher J. Dinsmore, Newton, MA (US);

Philip Jones, Houston, TX (US);

Inventors:

David Joseph Guerin, Natick, MA (US);

Jason D. Brubaker, Cambridge, MA (US);

Michelle Martinez, Medford, MA (US);

Joon O. Jung, Newton, MA (US);

Neville J. Anthony, Northborough, MA (US);

Mark E. Scott, Andover, MA (US);

Carolyn Michele Cammarano, Worcestor, MA (US);

Dawn Marie Mampreian Hoffman, Boston, MA (US);

Hyun Chong Woo, Natick, MA (US);

Christopher J. Dinsmore, Newton, MA (US);

Philip Jones, Houston, TX (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/90 (2006.01); A61K 31/519 (2006.01); C07D 487/00 (2006.01); C07D 471/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/519 (2013.01); C07D 519/00 (2013.01);
Abstract

The instant invention provides compounds of formula I which are Jak inhibitors, and as such are useful for the treatment of Jak-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.


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