The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 20, 2015
Filed:
Jun. 13, 2013
Applicant:
Portola Pharmaceuticals, Inc., South San Francisco, CA (US);
Inventors:
Shawn M. Bauer, Pacifica, CA (US);
Anjali Pandey, Fremont, CA (US);
Assignee:
Portola Pharmaceuticals, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/505 (2006.01); C07D 403/12 (2006.01); C07D 239/48 (2006.01); A61K 31/5377 (2006.01); C07D 413/12 (2006.01); C07D 403/14 (2006.01); C07D 417/12 (2006.01); C07D 413/14 (2006.01); C07D 401/12 (2006.01); A61K 31/506 (2006.01); A61K 31/5355 (2006.01); C07D 401/14 (2006.01); A61K 31/551 (2006.01); A61K 31/4985 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); C07D 239/48 (2013.01); A61K 31/5377 (2013.01); C07D 413/12 (2013.01); C07D 403/14 (2013.01); C07D 417/12 (2013.01); C07D 413/14 (2013.01); A61K 31/506 (2013.01); C07D 403/12 (2013.01); A61K 31/5355 (2013.01); A61K 31/505 (2013.01); C07D 401/14 (2013.01); A61K 31/551 (2013.01); A61K 31/4985 (2013.01);
Abstract
The present invention is directed to methods of inhibiting syk and/or JAK kinase activity, methods of inhibiting platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk and/or JAK kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma with compounds of the formula: and pharmaceutically acceptable tautomers, salts, or stereoisomers thereof.