The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 20, 2015
Filed:
Oct. 16, 2009
Applicants:
Shibo Jiang, Fresh Meadows, NY (US);
Zhi Qi, Guangdong, CN;
Chungen Pan, Fresh Medows, NY (US);
Inventors:
Assignee:
New York Bood Center, Inc., New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/21 (2006.01); A61P 31/18 (2006.01); C07K 14/005 (2006.01);
U.S. Cl.
CPC ...
A61K 39/21 (2013.01); C07K 14/005 (2013.01); C07K 2319/30 (2013.01); C07K 2319/40 (2013.01); C12N 2740/16122 (2013.01); C12N 2740/16134 (2013.01);
Abstract
Provided herein are immunogenic compositions comprising fusion proteins, the fusion proteins comprising lentivirus gp41 or a fragment thereof, a trimerization or oligomerization motif and an immunoenhancer that elicit potent and broad HIV neutralizing antibody responses in the immunized hosts. Also disclosed are methods of making and using the immunogenic compositions.