The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 13, 2015

Filed:

Dec. 16, 2010
Applicant:

David A. Wright, Livermore, CA (US);

Inventor:

David A. Wright, Livermore, CA (US);

Assignee:

Thermo Finnigan LLC, San Jose, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 30/72 (2006.01); G06F 17/40 (2006.01); G06F 19/00 (2011.01); B01D 59/44 (2006.01); G01N 15/02 (2006.01); G01N 30/86 (2006.01);
U.S. Cl.
CPC ...
G01N 30/8675 (2013.01); G01N 15/02 (2013.01); G01N 30/72 (2013.01); B01D 59/44 (2013.01); G06F 19/703 (2013.01); G06F 17/40 (2013.01); G06F 19/00 (2013.01); G01N 30/7266 (2013.01); G01N 30/8637 (2013.01); G01N 30/8641 (2013.01); G01N 30/8686 (2013.01);
Abstract

A method for matching precursor ions to product ions generated in a chromatography—mass spectrometry experiment comprises: choosing a time window defining a region of interest for precursor ion data and product ion data generated by the experiment; constructing a plurality of extracted ion chromatograms (XICs) for the precursor ion data and the product ion data within the region of interest; automatically detecting and characterizing chromatogram peaks within each XIC and automatically generating synthetic analytical fit peaks thereof; discarding a subset of the synthetic analytical peaks which do not satisfy noise reduction rules; performing a respective cross-correlation score calculation between each pair of synthetic analytical fit peaks; and recognizing matches between precursor ions and product ions based on the cross correlation scores.


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