The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 13, 2015
Filed:
Apr. 06, 2009
Applicants:
Kamil Koristek, Samotisky, CZ;
Pavel Hradil, Hlusovice, CZ;
Martin Grepl, Hlusovice, CZ;
Petr Slezar, Olomouc, CZ;
Inventors:
Kamil Koristek, Samotisky, CZ;
Pavel Hradil, Hlusovice, CZ;
Martin Grepl, Hlusovice, CZ;
Petr Slezar, Olomouc, CZ;
Assignee:
Farmak, A.S., Olomouc, CZ;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 333/58 (2006.01); C07D 333/60 (2006.01);
U.S. Cl.
CPC ...
C07D 333/58 (2013.01);
Abstract
A method of preparation of N-(1-benzo[b]thien-2-ylethyl)-N-hydroxyurea of formula (I) with the use of a reaction of 1-(benzo[b]thien-2-yl)-ethanol of formula (II) with hydroxyurea of formula (III) in organic solvents, organic acids, their mixtures or in mixtures thereof with water, being catalyzed by strongly acidic cation exchangers or various hydrogen sulphates.