The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 13, 2015
Filed:
Sep. 28, 2012
Applicant:
Isis Pharmaceuticals, Inc., Carlsbad, CA (US);
Inventors:
Sanjay Bhanot, Carlsbad, CA (US);
Xing Xian Yu, Carlsbad, CA (US);
Michael L. McCaleb, La Jolla, CA (US);
Assignee:
Isis Pharmaceuticals, Inc., Carlsbad, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); A61K 31/711 (2006.01); A61K 45/06 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C07H 21/04 (2013.01); A61K 31/711 (2013.01); A61K 45/06 (2013.01); C12N 15/1138 (2013.01); C12N 2310/11 (2013.01); C12N 2310/315 (2013.01); C12N 2310/323 (2013.01); C12N 2310/3231 (2013.01); C12N 2310/3341 (2013.01); C12N 2310/341 (2013.01); C12N 2310/346 (2013.01);
Abstract
Provided herein are methods, compounds, and compositions for reducing expression of fibroblast growth factor receptor 4 (FGFR4) mRNA and protein in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate a metabolic disease, or a symptom thereof.