The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8933117 B1

PDF
Full Text
Expired
Date of Patent:
Jan. 13, 2015

Filed:

Sep. 22, 2011
Applicants:

Nobuyuki Ohkawa, Tokyo, JP;

Kouki Iida, Tokyo, JP;

Takayoshi Nagasaki, Tokyo, JP;

Inventors:

Nobuyuki Ohkawa, Tokyo, JP;

Kouki Iida, Tokyo, JP;

Takayoshi Nagasaki, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/26 (2006.01); A61K 31/355 (2006.01); C07D 317/72 (2006.01); A61K 31/357 (2006.01);
U.S. Cl.
CPC ...
C07D 317/72 (2013.01); A61K 31/357 (2013.01);
Abstract

To provide potassium salts of substituted cycloalkene derivatives, which suppress the production of an inflammatory mediator caused by intracellular signal transduction or cell activation induced by endotoxin, and crystals thereof. The present invention provides potassium (2-chloro-4-fluorophenyl){[(2R,3R,8R)-7-(ethoxycarbonyl)-2,3-bis(hydroxymethyl)-1,4-dioxaspiro[4.5]deca-6-en-8-yl]sulfonyl}azanide and potassium (2-bromo-4-fluorophenyl){[(2R,3R,8R)-7-(ethoxycarbonyl)-2,3-bis(hydroxymethyl)-1,4-dioxaspiro[4.5]deca-6-en-8-yl]sulfonyl}azanide, each of which suppresses the production of an inflammatory mediator caused by intracellular signal transduction or cell activation induced by endotoxin, crystals thereof, and a pharmaceutical containing any of the same, and a prophylactic and/or therapeutic agent for sepsis containing any of the same.


Find Patent Forward Citations

Ohkawa, Nobuyuki. (2015). Crystals of substituted cycloalkene derivatives (U.S. Patent No. 8933117). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8933117

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