The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 13, 2015

Filed:

Jan. 19, 2012
Applicants:

Alejandro Crespo, Edison, NJ (US);

Ping Lan, Dayton, NJ (US);

Rudrajit Mal, Edison, NJ (US);

Anthony Ogawa, Mountainside, NJ (US);

Hong Shen, West Windsor, NJ (US);

Peter J. Sinclair, Scotch Plains, NJ (US);

Zhongxiang Sun, Edison, NJ (US);

Ellen K. Vande Bunte, Colts Neck, NJ (US);

Zhicai Wu, Montvale, NJ (US);

Kun Liu, Shanghai, CN;

Robert J. Devita, Westfield, NJ (US);

Dong-ming Shen, Edison, NJ (US);

Min Shu, Greenbrook, NJ (US);

John Qiang Tan, Westfield, NJ (US);

Changhe Qi, Shanghai, CN;

Yuguang Wang, Shanghai, CN;

Richard Beresis, Shanghai, CN;

Inventors:

Alejandro Crespo, Edison, NJ (US);

Ping Lan, Dayton, NJ (US);

Rudrajit Mal, Edison, NJ (US);

Anthony Ogawa, Mountainside, NJ (US);

Hong Shen, West Windsor, NJ (US);

Peter J. Sinclair, Scotch Plains, NJ (US);

Zhongxiang Sun, Edison, NJ (US);

Ellen K. Vande Bunte, Colts Neck, NJ (US);

Zhicai Wu, Montvale, NJ (US);

Kun Liu, Shanghai, CN;

Robert J. DeVita, Westfield, NJ (US);

Dong-Ming Shen, Edison, NJ (US);

Min Shu, Greenbrook, NJ (US);

John Qiang Tan, Westfield, NJ (US);

Changhe Qi, Shanghai, CN;

Yuguang Wang, Shanghai, CN;

Richard Beresis, Shanghai, CN;

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/416 (2006.01); C07D 231/56 (2006.01); A61K 31/405 (2006.01); A61K 31/404 (2006.01); C07D 403/06 (2006.01); C07D 209/08 (2006.01); C07D 209/10 (2006.01); A61K 31/4196 (2006.01); A61K 31/422 (2006.01); A61K 31/4245 (2006.01); A61K 45/06 (2006.01); C07D 413/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/405 (2013.01); A61K 31/404 (2013.01); A61K 31/416 (2013.01); C07D 231/56 (2013.01); C07D 403/06 (2013.01); C07D 209/08 (2013.01); C07D 209/10 (2013.01); A61K 31/4196 (2013.01); A61K 31/422 (2013.01); A61K 31/4245 (2013.01); A61K 45/06 (2013.01); C07D 413/06 (2013.01);
Abstract

Disclosed are the compounds of the Formula (I) as well as pharmaceutically acceptable salts thereof, which are useful for treating aldosterone-mediated diseases. The processes for preparing compounds of the Formula (I), the use for the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and the pharmaceutical compositions which comprise compounds of the formula (I) are disclosed too.


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