The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 13, 2015

Filed:

Sep. 05, 2012
Applicants:

Jun Cao, Changshu, CN;

Bernhard Erb, Gipf-Oberfrick, CH;

Robin Alec Fairhurst, Riehen, CH;

Arnaud Grandeury, Helfrantzkirch, FR;

Shinji Hatakeyama, Basel, CH;

Magdalena Koziczak-holbro, Basel, CH;

Xinzhong Lai, Changshu, CN;

Philipp Lustenberger, Basel, CH;

Bernd Riebesehl, Loerrach, DE;

Nicola Tufilli, Moehlin, CH;

Thomas Ullrich, Bottmingen, CH;

Xiang Wu, Changshu, CN;

Jianguang Zhou, Suzhou, CN;

Inventors:

Jun Cao, Changshu, CN;

Bernhard Erb, Gipf-Oberfrick, CH;

Robin Alec Fairhurst, Riehen, CH;

Arnaud Grandeury, Helfrantzkirch, FR;

Shinji Hatakeyama, Basel, CH;

Magdalena Koziczak-Holbro, Basel, CH;

Xinzhong Lai, Changshu, CN;

Philipp Lustenberger, Basel, CH;

Bernd Riebesehl, Loerrach, DE;

Nicola Tufilli, Moehlin, CH;

Thomas Ullrich, Bottmingen, CH;

Xiang Wu, Changshu, CN;

Jianguang Zhou, Suzhou, CN;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/78 (2006.01); A61K 31/425 (2006.01); C07D 277/62 (2006.01); C07D 277/68 (2006.01); C07D 327/04 (2006.01); C07D 343/00 (2006.01); C07D 327/10 (2006.01); C07D 339/02 (2006.01); C07D 341/00 (2006.01); C07D 409/00 (2006.01); C07D 411/00 (2006.01); C07D 495/00 (2006.01); C07D 497/00 (2006.01); A61K 31/428 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/428 (2013.01); C07D 277/68 (2013.01); A61K 45/06 (2013.01);
Abstract

The present invention provides a compound of formula (I) in free form or in pharmaceutically acceptable salt form a method for manufacturing the compound of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and pharmaceutical compositions.


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