The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 13, 2015

Filed:

Oct. 19, 2010
Applicants:

Dominik Feuerbach, Müllheim, DE;

Werner Müller, Gümligen, CH;

Bernard Lucien Roy, Fribourg, CH;

Thomas J. Troxler, Wahlen b. Laufen, CH;

Konstanze Hurth, Saint Louis, FR;

Mathias Frederiksen, Basel, CH;

Inventors:

Dominik Feuerbach, Müllheim, DE;

Werner Müller, Gümligen, CH;

Bernard Lucien Roy, Fribourg, CH;

Thomas J. Troxler, Wahlen b. Laufen, CH;

Konstanze Hurth, Saint Louis, FR;

Mathias Frederiksen, Basel, CH;

Assignee:

Novartis AG, Basel, CH;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); C07D 239/28 (2006.01); C07D 471/08 (2006.01); A61P 29/00 (2006.01); A61P 25/28 (2006.01); A61P 25/16 (2006.01); A61P 25/24 (2006.01);
U.S. Cl.
CPC ...
C07D 471/08 (2013.01);
Abstract

The present invention relates to 1-aza-bicycloalkyl derivatives of Formula (I); wherein the substituents are as defined in the specification, to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them. Formula (I), wherein A represents O or N(R); Y represents a group of formula, or wherein the left bond is attached to the A group and the right bond is attached to the R group; R represents a substituted or unsubstituted C-C, substituted or unsubstituted hetero-C-Caryl, a group N(R)(R), or a group N(R)(CHPR); R represent a hydrogen, C-Calkyl, or CF; Rrepresents hydrogen, C-Calkyl, or CF; Rrepresents hydrogen, C-Calkyl, or CF; Rrepresents a substituted or unsubstituted C-Caryl or a substituted or unsubstituted C-Cheteroaryl; in free base or acid addition salt form.


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