The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 13, 2015

Filed:

Nov. 06, 2009
Applicants:

John D. Crispino, Wilmette, IL (US);

Qiang Wen, Chicago, IL (US);

Zan Huang, Chicago, IL (US);

Andrew M. Stern, Boston, MA (US);

Robert J. Gould, Beverly, MA (US);

Inventors:

John D. Crispino, Wilmette, IL (US);

Qiang Wen, Chicago, IL (US);

Zan Huang, Chicago, IL (US);

Andrew M. Stern, Boston, MA (US);

Robert J. Gould, Beverly, MA (US);

Assignees:

Northwestern University, Evanston, IL (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/551 (2006.01); A61K 31/5513 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5513 (2013.01); A61K 31/551 (2013.01);
Abstract

Disclosed are methods for inducing polyploidization of megakaryocyte cells and for promoting differentiation of megakaryocyte cells into platelet-producing cells. The methods may be utilized for treating blood and bone marrow diseases and disorders in a subject in need thereof and for identifying agents for treating blood and bone marrow diseases and disorders.


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