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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8933016 B1

PDFFull Text
Expired
Date of Patent:
Jan. 13, 2015

Filed:

Jan. 18, 2013

Metallodrugs having improved pharmacological properties and methods of manufacture and use thereof

Applicant:

Metallopharm Llc, Delaware, OH (US);

Inventors:

James A. Cowan, Delaware, OH (US);

Ada S. Cowan, Delaware, OH (US);

Assignee:

MetalloPharm, LLC, Delaware, OH (US);

Attorneys:

Michael A. Whittaker

Yimei C. Hammond

Kremblas & Foster

Primary Examiner:

Karlheinz R Skowronek

Assistant Examiner:

Jia-Hai Lee

Int. Cl.
CPC ...
C07D 501/28 (2006.01); C07K 19/00 (2006.01); C07D 401/10 (2006.01); C07D 499/68 (2006.01); C07H 17/04 (2006.01); A61K 31/33 (2006.01); C07K 14/46 (2006.01); C07K 14/47 (2006.01); C07K 14/435 (2006.01);
U.S. Cl.
CPC ...
C07D 501/28 (2013.01); C07K 2319/20 (2013.01); C07K 2319/00 (2013.01); C07D 401/10 (2013.01); A61K 31/33 (2013.01); C07D 499/68 (2013.01); C07H 17/04 (2013.01); C07K 14/463 (2013.01); C07K 19/00 (2013.01); C07K 14/4723 (2013.01); C07K 14/43563 (2013.01);
Abstract

It is an object of the present invention to provide antimicrobial metallodrugs comprising an antimicrobial peptide ('AMP') and/or an antibiotic covalently bound to a metal binding moiety. These metallodrugs combine a metal binding domain which typically catalyzes oxido-reductase chemistry or acts as a Lewis-Acid catalyst, with a member of a diverse class of antimicrobial agents currently validated in preclinical and clinical settings for the treatment of a broad spectrum of pathogenic organisms.

Find Patent Forward Citations

Cowan, James. (2015). Metallodrugs having improved pharmacological properties and methods of manufacture and use thereof (U.S. Patent No. 8933016). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8933016

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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