The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 13, 2015
Filed:
Sep. 10, 2014
Applicant:
Biodesy, Inc., South San Francisco, CA (US);
Inventor:
Joshua S. Salafsky, South San Francisco, CA (US);
Assignee:
Biodesy, Inc., South San Francisco, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/573 (2006.01);
U.S. Cl.
CPC ...
G01N 33/573 (2013.01); G01N 2333/91205 (2013.01); G01N 2333/91215 (2013.01); G01N 2500/04 (2013.01);
Abstract
The present invention discloses, inter alia, methods for labeling a target protein with an SHG-active probe for detection by second harmonic or sum-frequency generation in order to identify agents which bind to an allosteric site on the target protein thereby altering its structural conformation.