The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 13, 2015
Filed:
Aug. 13, 2009
Sergey V. Paushkin, Belle Mead, NJ (US);
Nikolai A. Naryshkin, East Brunswick, NJ (US);
Ellen Welch, Califon, NJ (US);
Sergey V. Paushkin, Belle Mead, NJ (US);
Nikolai A. Naryshkin, East Brunswick, NJ (US);
Ellen Welch, Califon, NJ (US);
PTC Therapeutics, Inc., South Plainfield, NJ (US);
Abstract
The present invention relates to compounds that modulate ribosomal frameshifting and nucleic acid constructs for use in methods for identifying or validation of compounds that modulate ribosomal frameshifting. In particular, the present invention relates to the use of nucleic acid constructs to identify or validate compounds capable of modulating the efficiency of programmed ribosomal frameshifting and the use of compounds that modulate the efficiency of programmed ribosomal frameshifting to inhibit the replication or infectivity of viruses that employ programmed ribosomal frameshifting.