The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 13, 2015
Filed:
Mar. 11, 2013
Applicant:
Crucell Holland B.v., Leiden, NL;
Inventors:
Jerome H. H. V. Custers, Alphen aan den Rijn, NL;
Jort Vellinga, Leiden, NL;
Assignee:
Crucell Holland B.V., Leiden, NL;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/23 (2006.01); A61K 39/12 (2006.01); C12N 7/02 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); C12N 2760/16234 (2013.01); C12N 2760/16121 (2013.01); C12N 2750/14143 (2013.01); C12N 2760/16151 (2013.01); C12N 2710/10321 (2013.01); C12N 2710/10343 (2013.01);
Abstract
Described is a composition comprising a plurality of recombinant adenovirus particles, being a recombinant human adenovirus of serotype 5, 26, 34, 35, 48, 49 or 50, or a recombinant simian adenovirus, characterized in that the genomes of essentially all adenovirus particles in the composition comprise as the 5' terminal nucleotides the nucleotide sequence: CTATCTAT (nucleotides 1-8 of SEQ ID NO:7). Also described are methods to produce such compositions.