The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 13, 2015
Filed:
Feb. 25, 2004
Applicants:
Bjarne Bogen, Snarøya, NO;
Agnete Fredriksen Brunsvik, Rælingen, NO;
Inger Sandlie, Oslo, NO;
Inventors:
Assignee:
Vaccibody AS, Oslo, NO;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); A61K 39/12 (2006.01); A61K 39/21 (2006.01); C07K 16/28 (2006.01); C07K 16/44 (2006.01); A61K 39/00 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2833 (2013.01); C07K 16/44 (2013.01); A61K 2039/505 (2013.01); A61K 2039/54 (2013.01); C07K 2317/31 (2013.01); C07K 2317/622 (2013.01);
Abstract
Recombinant antibody-based molecules that trigger both T-cell and B-cell immune responses are disclosed. The recombinant molecules are comprised by at least one targeting unit and at least one antigenic unit connected through a dimerization motif. Also disclosed are nucleic acid molecules encoding the recombinant antibody-based molecule and methods of treating multiple myeloma or lymphoma in a patient using the recombinant antibody-based molecules or the nucleic acid molecules.