The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 13, 2015
Filed:
May. 22, 2012
Gang Chen, Redondo Beach, CA (US);
Umesh B. Gangadharmath, Los Angeles, CA (US);
Dhanalakshmi Kasi, Los Angeles, CA (US);
Anjana Sinha, San Diego, CA (US);
Wei Zhang, Los Angeles, CA (US);
Kai Chen, San Gabriel, CA (US);
Vani P. Mocharla, Los Angeles, CA (US);
Gang Chen, Redondo Beach, CA (US);
Umesh B. Gangadharmath, Los Angeles, CA (US);
Dhanalakshmi Kasi, Los Angeles, CA (US);
Anjana Sinha, San Diego, CA (US);
Wei Zhang, Los Angeles, CA (US);
Kai Chen, San Gabriel, CA (US);
Vani P. Mocharla, Los Angeles, CA (US);
Eli Lilly and Company, Indianapolis, IN (US);
Abstract
Disclosed here in are compounds and methods of diagnosing Alzheimer's Disease or a predisposition thereto in a mammal, the method comprising administering to the mammal a diagnostically effective amount of a radiolabeled compound, wherein the compound is selected from the group consisting of radiolabeled carbazoles and derivatives thereof and triazoles derivatives, allowing the compound to distribute into the brain tissue, and imaging the brain tissue, wherein an increase in binding of the compound to the brain tissue compared to a normal control level of binding indicates that the mammal is suffering from or is at risk of developing Alzheimer's Disease.