The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2015
Filed:
Feb. 18, 2011
Applicants:
Duck Jong Han, Seoul, KR;
Sung-eun Yoo, Chungcheongnam-do, KR;
Jeehee Suh, Daejeon, KR;
Inventors:
Assignee:
The Asan Foundation, Seoul, KR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 321/00 (2006.01); C07C 235/56 (2006.01); C07C 233/32 (2006.01); A61K 45/06 (2006.01); C07C 271/24 (2006.01); A61K 31/165 (2006.01);
U.S. Cl.
CPC ...
C07C 271/24 (2013.01); C07C 2101/14 (2013.01); C07C 2102/08 (2013.01); C07C 235/56 (2013.01); C07C 233/32 (2013.01); C07C 2103/18 (2013.01); C07C 2102/10 (2013.01); C07C 2103/34 (2013.01); C07C 2101/08 (2013.01); A61K 45/06 (2013.01); A61K 31/165 (2013.01);
Abstract
The present invention relates to colchicine derivatives expressed in chemical formula 1, or to pharmaceutically acceptable salts thereof, to a method for preparing said derivatives, and to a pharmaceutical composition comprising said derivatives. The colchicine derivatives according to the present invention exhibit superior immunomodulatory effects as compared with conventional immunomodulators or colchicines, and therefore can be valuably used as an immunomodulator for modulating an acute or chronic immune response in organ transplantation.