The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 06, 2015

Filed:

Nov. 18, 2013
Applicant:

Enanta Pharmaceuticals, Inc., Watertown, MA (US);

Inventors:

Yao-Ling Qiu, Andover, MA (US);

Xiaowen Peng, Cambridge, MA (US);

In Jong Kim, Lexington, MA (US);

Hui Cao, Belmont, MA (US);

Datong Tang, Newton, MA (US);

Yat Sun Or, Watertown, MA (US);

Guoqiang Wang, Belmont, MA (US);

Guoyou Xu, Framingham, MA (US);

Assignee:

Enanta Pharmaceuticals, Inc., Watertown, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/54 (2006.01);
U.S. Cl.
CPC ...
C07D 209/54 (2013.01);
Abstract

The present invention relates generally to an improved process for the preparation of 5-azaspiro[2.4]heptane-6-carboxylic acid and its derivatives which are useful intermediates in the synthesis of biologically active molecules, especially in the synthesis of hepatits C virus NS5A inhibitors. In particular, the present invention relates to processes and intermediates for the preparation of compounds of formulae (Ia), (Ib) and (Ic):


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