The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2015
Filed:
Jun. 07, 2007
Tadayoshi Okumura, Hirakata, JP;
Mikio Nishizawa, Ibaraki, JP;
Yasuo Kamiyama, Takatsuki, JP;
Koji Wakame, Sapporo, JP;
Takehito Miura, Sapporo, JP;
Tadayoshi Okumura, Hirakata, JP;
Mikio Nishizawa, Ibaraki, JP;
Yasuo Kamiyama, Takatsuki, JP;
Koji Wakame, Sapporo, JP;
Takehito Miura, Sapporo, JP;
Amino Up Chemical Co., Ltd, Hokkaido, JP;
Kansai Medical University, Osaka, JP;
Abstract
The invention relates to sense oligonucleotide having a sequence complementary to a single-stranded RNA (antisense transcript) having a sequence complementary to mRNA of iNOS gene in order to control expression of iNOS (inducible nitric oxide synthase). The sense oligonucleotide of the present invention can control expression of iNOS and is useful for biological defense and treatment and prevention of diseases related to excessive production of NO, such as cancerogenesis, inflammatory disease, endotoxin shock by bacterial infection and the like.