The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 06, 2015

Filed:

Mar. 07, 2013
Applicant:

Rigel Pharmaceuticals, Inc., South San Francisco, CA (US);

Inventors:

Dane Goff, Redwood City, CA (US);

Donald G. Payan, Hillsborough, CA (US);

Sylvia Braselmann, San Francisco, CA (US);

Assignee:

Rigel Pharmaceuticals, Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/14 (2006.01); C07D 471/04 (2006.01); C07D 471/14 (2006.01); C07D 471/22 (2006.01); C07D 487/04 (2006.01); C07D 491/22 (2006.01); A61K 31/437 (2006.01); C07D 513/04 (2006.01); C07D 491/147 (2006.01); C07D 495/14 (2006.01); C07D 495/22 (2006.01); C07D 498/04 (2006.01); C07D 513/14 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 471/14 (2013.01); C07D 487/14 (2013.01); C07D 513/04 (2013.01); C07D 471/22 (2013.01); C07D 491/147 (2013.01); C07D 491/22 (2013.01); C07D 495/14 (2013.01); C07D 495/22 (2013.01); C07D 498/04 (2013.01); C07D 513/14 (2013.01);
Abstract

Disclosed embodiments concern polycyclic alkaloid compounds and methods for their use and synthesis. Particular embodiments concern polycyclic alkaloids having a fused, six-membered ring, while other embodiments concern polycyclic alkaloids having a fused, five-membered ring. Methods for making the polycyclic alkaloids are disclosed, as well as methods for their use as prophylactics or treatments for certain diseases. Also disclosed are pharmaceutical compositions comprising the polycyclic alkaloids and their use.


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