The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 06, 2015

Filed:

May. 14, 2012
Applicants:

Francesco Fontana, Vicenza, IT;

Alessandro Leganza, Vicenza, IT;

Sergio Osti, Vicenza, IT;

Inventors:

Francesco Fontana, Vicenza, IT;

Alessandro Leganza, Vicenza, IT;

Sergio Osti, Vicenza, IT;

Assignee:

F.I.S.—Fabbrica Italiana Sintetici S.p.A., Montecchio Maggiore (VI), IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); C07D 405/10 (2006.01); C07D 239/94 (2006.01); G01N 30/06 (2006.01); A61P 35/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Impurities of lapatinib such as N-{3-chloro-4-[(2-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)furan-2-yl]quinazoline-4-amine compound of formula (I) or a salt thereof: and analytical methods for identifying and quantifying such impurities of Lapatinib and salts thereof are provided. Also provided is Lapatinib containing less than about 0.05 percent of this and related impurities and methods for preparing such pure forms of Lapatinib.


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