The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 06, 2015

Filed:

Jan. 13, 2012
Applicants:

Weiwen Ying, Lexington, MA (US);

David James, Boston, MA (US);

Shijie Zhang, Nashua, NH (US);

Junghyun Chae, Youngdengpo-Yu, KR;

Teresa Kowalczyk-przewloka, Tewksbury, MA (US);

Howard P. NG, Cedar Knolls, NJ (US);

Hao LI, Brookline, MA (US);

Zachary Demko, Los Altos, CA (US);

Dinesh U. Chimmanamada, Arlington, MA (US);

Chi-wan Lee, Grafton, MA (US);

Zhenjian Du, Northborough, MA (US);

Kevin Foley, Landsdale, PA (US);

Minghu Song, Chester Springs, PA (US);

Lijun Sun, Harvard, MA (US);

Keizo Koya, Chestnut Hill, MA (US);

Dan Zhou, Lexington, MA (US);

Shuzhen Qin, West Roxbury, MA (US);

Inventors:

Weiwen Ying, Lexington, MA (US);

David James, Boston, MA (US);

Shijie Zhang, Nashua, NH (US);

Junghyun Chae, Youngdengpo-Yu, KR;

Teresa Kowalczyk-Przewloka, Tewksbury, MA (US);

Howard P. Ng, Cedar Knolls, NJ (US);

Hao Li, Brookline, MA (US);

Zachary Demko, Los Altos, CA (US);

Dinesh U. Chimmanamada, Arlington, MA (US);

Chi-wan Lee, Grafton, MA (US);

Zhenjian Du, Northborough, MA (US);

Kevin Foley, Landsdale, PA (US);

Minghu Song, Chester Springs, PA (US);

Lijun Sun, Harvard, MA (US);

Keizo Koya, Chestnut Hill, MA (US);

Dan Zhou, Lexington, MA (US);

Shuzhen Qin, West Roxbury, MA (US);

Assignee:

Synta Pharmaceuticals Corp., Lexington, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 249/12 (2006.01); C07D 401/04 (2006.01); C07D 405/10 (2006.01); C07D 417/04 (2006.01); C07D 405/14 (2006.01); C07D 409/04 (2006.01); A61K 31/5377 (2006.01); A61P 35/00 (2006.01); C07D 405/04 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01);
U.S. Cl.
CPC ...
C07D 409/04 (2013.01); C07D 405/04 (2013.01); C07D 249/12 (2013.01); C07D 417/04 (2013.01); C07D 405/10 (2013.01); C07D 403/04 (2013.01); C07D 403/14 (2013.01); C07D 401/04 (2013.01); C07D 405/14 (2013.01);
Abstract

The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.


Find Patent Forward Citations

Loading…