The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2015
Filed:
Jan. 31, 2007
Gunther Zischinsky, Berlin, DE;
Roland Stragies, Berlin, DE;
Frank Osterkamp, Berlin, DE;
Dirk Scharn, Berlin, DE;
Gerd Hummel, Berlin, DE;
Holger Kalkhof, Berlin, DE;
Grit Zahn, Berlin, DE;
Doerte Vossmeyer, Berlin, DE;
Claudia Christner-albrecht, Berlin, DE;
Ulrich Reineke, Berlin, DE;
Gunther Zischinsky, Berlin, DE;
Roland Stragies, Berlin, DE;
Frank Osterkamp, Berlin, DE;
Dirk Scharn, Berlin, DE;
Gerd Hummel, Berlin, DE;
Holger Kalkhof, Berlin, DE;
Grit Zahn, Berlin, DE;
Doerte Vossmeyer, Berlin, DE;
Claudia Christner-Albrecht, Berlin, DE;
Ulrich Reineke, Berlin, DE;
Shire Orphan Therapies GmbH, Berlin, DE;
Abstract
The present invention is related to a compound of formula (I), wherein A is a nonaromatic heterocyclic ring, Ar is either absent or phenylene; Ψ is a radical of formula (II), Ris a hydrophobic moiety; and G is a radical containing one or more moieties selected from the group consisting of NH, OH and a basic moiety. The compounds are inhibitors of integrins, especially antagonists of the fibronectin receptor alpha5beta1, useful as anti-angiogenic agents.