The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2015
Filed:
Sep. 17, 2012
Applicant:
Sigma-tau Industrie Farmaceutiche Riunite S.p.a., Rome, IT;
Inventors:
Giuseppe Giannini, Pomezia (RM), IT;
Walter Cabri, Rozzano (MI), IT;
Gianfranco Battistuzzi, Rome, IT;
Davide Vignola, Aprilia (LT), IT;
Nicola Fanto', Pomezia (RM), IT;
Claudio Pisano, Aprilia (LT), IT;
Loredana Vesci, Rome, IT;
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/397 (2006.01); A61K 31/4412 (2006.01); C07D 205/08 (2006.01); C07D 211/40 (2006.01); C07D 207/24 (2006.01); C07D 213/69 (2006.01); C07D 401/04 (2006.01); C07D 207/277 (2006.01); C07D 207/28 (2006.01); C07D 211/78 (2006.01); C07D 207/46 (2006.01); C07D 211/94 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
C07D 213/69 (2013.01); C07D 401/04 (2013.01); C07D 205/08 (2013.01); C07D 207/277 (2013.01); C07D 207/28 (2013.01); C07D 211/78 (2013.01); C07D 207/46 (2013.01); C07D 211/94 (2013.01); C07D 401/12 (2013.01);
Abstract
The present invention relates to novel amide compounds of Formula (I), and their use as anti-tumoral and pro-apoptotic agents. The invention includes the use of such compounds in medicine, in relation to cancer disease as well as other diseases where an inhibition of HDAC is responsive, and the pharmaceutical composition containing such compounds.