The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 06, 2015

Filed:

Sep. 13, 2012
Applicants:

Toshihiko Kuroiwa, Osaka, JP;

Yoshinaga Kajimoto, Takatsuki, JP;

Takahiro Masubuchi, Yamatokooriyama, JP;

Masahiro Ishizuka, Tokyo, JP;

Tohru Tanaka, Tokyo, JP;

Inventors:

Toshihiko Kuroiwa, Osaka, JP;

Yoshinaga Kajimoto, Takatsuki, JP;

Takahiro Masubuchi, Yamatokooriyama, JP;

Masahiro Ishizuka, Tokyo, JP;

Tohru Tanaka, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/555 (2006.01); A61K 31/195 (2006.01); A61K 31/295 (2006.01); A61K 31/197 (2006.01); A61K 31/198 (2006.01); A61K 33/26 (2006.01); A61K 45/06 (2006.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/295 (2013.01); A61K 31/197 (2013.01); A61K 31/198 (2013.01); A61K 33/26 (2013.01); A61K 45/06 (2013.01); A61K 49/0008 (2013.01);
Abstract

To provide a therapeutic agent and a diagnostic agent for mitochondrial dysfunction brain diseases including cerebral infarction as a representative. A therapeutic agent for a mitochondrial dysfunction brain disease, which comprises (A) δ-aminolevulinic acid represented by the formula (1), a derivative thereof, or a salt thereof and (B) an iron compound in combination.RRNCHCOCHCHCOR  (1)wherein Rand Reach independently represents a hydrogen atom, an alkyl group, an acyl group, an alkoxycarbonyl group, an aryl group, or an aralkyl group; and Rrepresents a hydroxy group, an alkoxy group, an acyloxy group, an alkoxycarbonyloxy group, an aryloxy group, an aralkyloxy group, or an amino group.


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