The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 06, 2015

Filed:

May. 21, 2010
Applicants:

Barbara Valsasina, Milan, IT;

Italo Beria, Nerviano, IT;

Antonella Ciavolella, Bizzarone, IT;

Dario Ballinari, San Donato Milanese, IT;

Enrico Pesenti, Parabiago, IT;

Juergen Moll, Appiano Gentile, IT;

Mara Emanuela Casnaghi, Nerviano, IT;

Alessandro Luciano Croci, Nerviano, IT;

Inventors:

Barbara Valsasina, Milan, IT;

Italo Beria, Nerviano, IT;

Antonella Ciavolella, Bizzarone, IT;

Dario Ballinari, San Donato Milanese, IT;

Enrico Pesenti, Parabiago, IT;

Valter Domenico Croci, Nerviano, IT;

Juergen Moll, Appiano Gentile, IT;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/54 (2006.01); C07D 239/42 (2006.01); C07D 401/04 (2006.01); C07D 471/22 (2006.01); C07D 487/04 (2006.01); A61K 31/515 (2006.01); A61K 45/06 (2006.01); A61K 31/282 (2006.01); A61K 31/337 (2006.01); A61K 31/4412 (2006.01); A61K 31/4745 (2006.01); A61K 31/4965 (2006.01); A61K 31/506 (2006.01); A61K 31/513 (2006.01); A61K 31/519 (2006.01); A61K 31/704 (2006.01); A61K 31/7068 (2006.01); A61K 33/24 (2006.01);
U.S. Cl.
CPC ...
A61K 45/06 (2013.01); A61K 31/282 (2013.01); A61K 31/337 (2013.01); A61K 31/4412 (2013.01); A61K 31/4745 (2013.01); A61K 31/4965 (2013.01); A61K 31/506 (2013.01); A61K 31/513 (2013.01); A61K 31/519 (2013.01); A61K 31/704 (2013.01); A61K 31/7068 (2013.01); A61K 33/24 (2013.01);
Abstract

The present invention provides a combination comprising (a) a compound of formula (I) and (b) one or more antineoplastic agents selected from the group consisting of an antimetabolite agent, analkylating or alkylating-like agent, an intercalating agent, a topoisomerase I or II inhibitor, an antimitotic agent, a kinase inhibitor, a proteasome inhibitor and an antibody inhibiting a growth factor or its receptor, wherein active ingredients of the combination are present in each case in free form or in the form of a pharmaceutically acceptable salt or any hydrate or solvate thereof, useful in the treatment of tumors.


Find Patent Forward Citations

Loading…