The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2015
Filed:
May. 20, 2009
Hua Shi, Ithaca, NY (US);
Albert J. T. Millis, Schenectady, NY (US);
Kimi Nishikawa, Greenwich, NY (US);
Prabhat Kumar Mallik, Watervliet, NY (US);
Hua Shi, Ithaca, NY (US);
Albert J. T. Millis, Schenectady, NY (US);
Kimi Nishikawa, Greenwich, NY (US);
Prabhat Kumar Mallik, Watervliet, NY (US);
The Research Foundation of State University of New York, Albany, NY (US);
Abstract
This invention relates to nucleic acid aptamers that recognize and bind the complement protein C3 or its biologically active proteolytic products and methods of their use. Particularly preferred are bi-functional aptamer construct that binding specifically with C3b or iC3b, and another target protein. Use of these molecular constructs for commandeering the opsonization process is also described herein.