The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2015
Filed:
Oct. 20, 2009
Applicants:
Robert Falconer, Nab Wood, GB;
Jason Gill, Rothwell Haigh, GB;
Jennifer Atkinson, Needingworth, GB;
Paul Loadman, Bradford, GB;
Michael Bibby, Eldwick, GB;
Laurence Patterson, Bingley, GB;
Inventors:
Robert Falconer, Nab Wood, GB;
Jason Gill, Rothwell Haigh, GB;
Jennifer Atkinson, Needingworth, GB;
Paul Loadman, Bradford, GB;
Michael Bibby, Eldwick, GB;
Laurence Patterson, Bingley, GB;
Assignee:
Incanthera Limited, Bradford, GB;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/03 (2006.01); C07K 7/00 (2006.01); A61K 47/48 (2006.01); C07K 7/06 (2006.01);
U.S. Cl.
CPC ...
C07K 7/06 (2013.01); A61K 47/481 (2013.01); A61K 47/48215 (2013.01); A61K 47/48338 (2013.01);
Abstract
The present invention relates to prodrugs of vascular disrupting agents comprising a vascular disrupting agent (VDA) associated with a matrix metalloproteinase (MMP) proteolytic cleavage site and to the use of such prodrugs in the targeted treatment of cancer.