The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2015
Filed:
Oct. 17, 2008
Applicant:
Wing L. Sung, Gloucester, CA;
Inventor:
Wing L. Sung, Gloucester, CA;
Assignee:
National Research Council Canada, Ottawa, ON, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/24 (2006.01); D21H 17/00 (2006.01); D21C 5/00 (2006.01); D21C 9/10 (2006.01);
U.S. Cl.
CPC ...
C12N 9/2482 (2013.01); D21C 9/1036 (2013.01); D21H 17/005 (2013.01); C12Y 302/01008 (2013.01); D21C 5/005 (2013.01);
Abstract
A modified Family 11 xylanase enzyme comprising cysteine residues at positions 99 and 118 to form an intramolecular disulfide bond is provided. The modified xylanase is produced by substitution of an amino acid at position 99, 118 or both positions 99 and 118 with a cysteine to produce the intramolecular disulfide bond. Xylanases of the invention display improved thermophilicity, alkalophilicity or thermostability relative to wild-type xylanases. Such xylanases find use in a variety of applications in industry that require enzyme activities at temperatures and/or pH values above that of the native enzyme.