The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 06, 2015

Filed:

Oct. 02, 2012
Applicant:

Fresenius Kabi Oncology Limited, Gurgaon, Haryana, IN;

Inventors:

Anand C. Burman, Ghaziabad, IN;

Rama Mukherjee, Ghaziabad, IN;

Dhiraj Khattar, Ghaziabad, IN;

Sanjoy Mullick, Ghaziabad, IN;

Manu Jaggi, Ghaziabad, IN;

Manoj Kumar Singh, Ghaziabad, IN;

Mukesh Kumar, Ghaziabad, IN;

Deepak Prusthy, Ghaziabad, IN;

Pawan Kumar Gupta, Ghaziabad, IN;

Rajendran Praveen, Ghaziabad, IN;

Shobhit Singh, Ghaziabad, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/30 (2006.01); A61K 47/32 (2006.01); C08F 220/56 (2006.01); C08F 222/12 (2006.01); C08F 226/10 (2006.01); C08F 222/38 (2006.01);
U.S. Cl.
CPC ...
A61K 47/32 (2013.01); C08F 220/56 (2013.01); C08F 222/12 (2013.01); C08F 226/10 (2013.01); C08F 222/385 (2013.01);
Abstract

The invention relates to a biocompatible, non-biodegradable, and non-toxic polymer of formula (I), comprising of three monomeric units, selected from 1-Vinylpyrrolidne (VP), N-Isopropylactylamide (NIPAM), and ester of Maleic anhydride and Polyethylene glycol (MPEG), cross-linked with a bi-functional vinyl derivative, of high purity and substantially free of respective toxic monomeric contaminants, and a process for preparation thereof. The invention further relates to nanoparticulate pharmaceutical compositions of poorly water-soluble drugs or compounds comprising the polymer of the invention, which are safe, less-toxic and convenient for bedside administration to patients in need thereof. Furthermore, the invention relates to a highly selective method for preparation of nanoparticulate pharmaceutical compositions of poorly water-soluble drugs or compounds.


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