The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 06, 2015
Filed:
Feb. 24, 2010
Zoltan Toelgyesi, Tata, HU;
Zsolt Zsigmond, Maglod, HU;
Gyoergy Ujfalussy, Budapest, HU;
Magdolna Leventiszne Huszar, Budapest, HU;
Peter Tonka-nagy, Budapest, HU;
Monika Agyagos, Sajoszentpeter, HU;
Zoltan Toelgyesi, Tata, HU;
Zsolt Zsigmond, Maglod, HU;
Gyoergy Ujfalussy, Budapest, HU;
Magdolna Leventiszne Huszar, Budapest, HU;
Peter Tonka-Nagy, Budapest, HU;
Monika Agyagos, Sajoszentpeter, HU;
Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszventarsasag, Budapest, HU;
Abstract
The present invention relates to a process for manufacturing microcrystalline ezetimibe containing granulate, wherein a) ezetimibe is dissolved; b) the dissolved ezetimibe is precipitated with water, which if necessary contains pharmaceutical excipients, preferably lauryl-sulfate derivatives, and c) granulates are formed from the obtained suspension by spraying the suspension onto pharmaceutical excipients. A further aspect of the present invention is the granulate obtained by the present process and the pharmaceutical composition containing such granulate.